Preparative - HPLC Columns

Explore our range of Prep-HPLC Columns

Quick Selection Guide - Choose your right pick as per your application

PurePhase Prep-HPLC Columns is specifically designed for high-throughput sample preparation, capable of purifying products ranging from milligram to gram quantities. The column offers multiple diameter specifications suitable for various preparative sample types, including high-throughput samples obtained during drug discovery, laboratory-scale preparations, and even pilot-scale sample production. Available in three inner diameters (10mm, 20mm, and 30mm) for semi-preparative to preparative chromatography, the columns are 50-250 mm in length. Available in particle sizes of 5 µm and 10 µm, these chromatography columns demonstrate exceptional column efficiency across all dimensions.

Advantages of PurePhase Prep-HPLC Columns:

• High sample yield, high purity samples were obtained, and the recovery rate was high.

• Easy conversion from 4.6 mm inner diameter to 50 mm inner diameter chromatography column for rapid method development conversion.

• At the same time, the 20mm inner diameter card sleeve column is high flux to achieve rapid purification.

• Under the condition of pH 12, it has excellent chromatographic column stability.

• Better separation efficiency and easy to linear amplification

• PurePhase Prep-HPLC Columns prepared by PurePhase Particle Technology is equipped with a preparation and protection column according to different inner diameter chromatography column specifications.

The column has a bonded stationary phase suitable for the purification of various non-polar and polar compounds, and also provides an unbonded silica gel chromatography column.

Performance characteristics of column packing Prep-HPLC Columns

Matrix characteristics

• The matrix of Morphling® preparation column is ultra-high purity full porous spherical silica gel (purity> 99.999%)

• Uniform pore size distribution and uniform particle size distribution

• Ensure the inertness and uniformity of the silicone surface by a unique surface modification method

• Large specific surface area (320m2/g), which has a strong retention capacity for hydrophobic and polar compounds

• Good mechanical stability, high pressure strength

Bonding Characteristics:

• Unique bonding technology, high bonding phase coverage

• The unique fully double-sealed tail technology can eliminate the residual silanol effect to the maximum extent, and has a good peak shape for the separation of basic and strongly polar compounds

• Fillers with particle sizes of 5um and 10um provide more options

Overall characteristics

• The same as the packing material used in the analysis column to ensure good reproducibility of the analysis scale and preparation scale;

• The unique column installation technology and 316L stainless steel column tube ensure the stability of the column bed;

• The theoretical number of plates is 40,000/m for 10um, and the theoretical number of plates is more than 80,000/m for 5um. The symmetry value of the peak is 0.95~1.25;

• The range of key bonding phase selection is wide, including positive phase SiO2 silica gel column, reverse phase WD-C18, AQ-C18, WD-C8, WD-C4;

Column Types and Ordering Info

Prep-HPLC Columns